Evidence map›Paper›PMID 42605315›Full record

ArticlePatient preference and adherence2026

Predictors of Beliefs About Medicines in Patients with Psychotic Disorders - A Longitudinal Observational Study in Mental Health Services.

Klara Skaare-Fatland, Monica Hermann, Miriam Hartveit, Jörg Assmus, Karin Drivenes, Torleif Ruud, Robert Horne, Robert E Drake, Vegard Øksendal Haaland, Eva Biringer

Abstract read
In one paragraph

Article in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Klara Skaare-FatlandDepartment of Research and Innovation, Fonna Hospital Trust, Haugesund, Norway.ORCID 0000-0001-9956-0558
Monica HermannDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Stord, Norway.ORCID 0000-0002-8006-3591
Miriam HartveitDepartment of Research and Innovation, Fonna Hospital Trust, Haugesund, Norway.
Jörg AssmusCompetence Centre for Clinical Research, Bergen Hospital Trust, Bergen, Norway.ORCID 0000-0002-1688-8556
Karin DrivenesDivision of Mental Health, Sørlandet Hospital Trust, Kristiansand, Norway.ORCID 0000-0003-4550-8740
Torleif RuudR&D Department Mental Health, Akershus University Hospital Trust, Lørenskog, Norway.ORCID 0000-0002-4821-1267
Robert HorneCentre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, UK.
Robert E DrakeDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA.
Vegard Øksendal HaalandDivision of Mental Health, Sørlandet Hospital Trust, Kristiansand, Norway.
Eva BiringerDepartment of Research and Innovation, Fonna Hospital Trust, Haugesund, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Patients' necessity beliefs and concerns about antipsychotic medication may influence medication adherence. This study aimed to identify factors predicting necessity beliefs and concerns about antipsychotic medication. Patients and Methods: This longitudinal study included patients with psychotic disorders from 31 Norwegian specialist mental health care units at baseline (0 months; N=310) and 12 months (n=151), reflecting attrition. We investigated associations between patients' sociodemographic and clinical characteristics, their perceptions of medication support (MedSupport questionnaire), and their medication necessity beliefs and concerns (Beliefs about Medicines Questionnaire; BMQ) at baseline. We assessed change in BMQ subscales from baseline to 12 months and factors associated with the change. The data were analyzed using linear mixed-effects models. Results: At baseline, higher MedSupport scores were associated with higher BMQ-Necessity (β=0.18 (95% confidence interval (CI)=0.04 to 0.33)) and lower BMQ-Concerns (β=-0.29 (95% CI=-0.42 to -0.16)) subscales. Higher educational level and higher number of psychotropic medications were associated with higher BMQ-Necessity. Higher symptom load and medication side effects were associated with higher BMQ-Concerns. Patients' beliefs about their medications became more negative over time, ie BMQ-Necessity scores decreased (-0.35 (95% CI=-0.60 to -0.11)) and BMQ-Concerns increased (0.25 (95% CI=0.05 to 0.45)). Higher dose of psychotropic medications at baseline and female sex was associated with an increase in BMQ-Necessity. A higher number of antipsychotic medications was associated with an increase in BMQ-Concerns from baseline to 12 months. Conclusion: Patients who experienced better medication support had significantly more positive medication beliefs at study start. Patients' views about their medications became significantly more negative over the one-year follow-up, highlighting the potential need for clinicians to provide follow-up support to address the doubts and concerns that might emerge over the course of treatment.

Indexed as

antipsychotic agentsattitudesbeliefs about medicines questionnairepsychiatrypsychosispsychotropic drugs

Identifiers

PMID42605315
PMCPMC13477654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.