Evidence map›Paper›PMID 42605125›Full record

ArticleBrain and behavior2026

Research Evolution and Frontiers in Glial Scar and Spinal Cord Injury Research: A Bibliometric Perspective.

Shanyong Zhang, Renfeng Zhang, Yuan Qu, Tingting Hou

Abstract read
In one paragraph

Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shanyong ZhangOrthopedics Department, The Second Hospital of Jilin University, Changchun, Jilin, China.
Renfeng ZhangOrthopedics Department, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yuan QuOrthopedics Department, The Second Hospital of Jilin University, Changchun, Jilin, China.
Tingting HouOrthopedics Department, The Second Hospital of Jilin University, Changchun, Jilin, China.

Funding

Science and Technology Research Project of the Education Department of Jilin Province JJKH20241333KJ
6 · The paper itself

Abstract

introductionGlial scars play a key role in the pathophysiology of spinal cord injury. This study aims to systematically analyze global research trends and advances on glial scars in spinal cord injury through bibliometric methods.

methodA comprehensive literature search was performed in the Web of Science Core Collection. Bibliometric analysis using VOSviewer, CiteSpace, and the R package Bibliometrix evaluated publication output, citation patterns, author and institutional contributions, international collaboration, journal impact, keyword co-occurrence, and emerging research themes.

resultsThe analysis encompassed 1293 articles on glial scars and spinal cord injury, authored by 7219 researchers from 4185 institutions across 51 countries. China led with 487 publications (37.7%), followed by the USA with 316 articles and the highest citation count of 27,628. Among institutions, the Chinese Academy of Sciences demonstrated the strongest collaborative network (total link strength = 32). The Journal of Neuroscience stood out as the most influential journal, publishing 64 articles and receiving 5703 citations. Keyword co-occurrence analysis identified five thematic clusters: Injury Responses and Inflammatory Mechanisms; Glial Scar Biology and Central Nervous System Microenvironment; Axonal Regeneration and Inhibitory Molecules; Cell-Based Therapeutic Strategies; and Proteoglycan-Related Topics. Burst keyword analysis showed a recent emphasis on terms such as "inflammation," "recovery," "delivery," and "pathway."

conclusionThis bibliometric study highlights the substantial growth and diversification of research on glial scars and spinal cord injuries in recent decades. The field is increasingly adopting interdisciplinary approaches and strengthening international collaboration, offering valuable insights into future research directions and potential clinical applications.

Indexed as

BibliometricsBiomedical ResearchCicatrixNeurogliaSpinal Cord InjuriesAnimalsHumansBibliometricsglial scarinflammationneural regenerationresearch trendsspinal cord Injury

Identifiers

PMID42605125
PMCPMC13478572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.