Evidence map›Paper›PMID 42604987›Full record

ArticleJournal of clinical apheresis2026

Therapeutic Plasma Exchange for Complicated Hyperthyroidism: A Case Series.

Hen Huu Phan, Thien Quoc Lam, Minh Duc Do

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Journal of clinical apheresis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hen Huu PhanDepartment of Endocrinology, Cho Ray Hospital, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0009-0002-4898-0987
Thien Quoc LamDepartment of Endocrinology, Cho Ray Hospital, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0009-0000-1001-413X
Minh Duc DoCenter for Molecular Biomedicine, University of Medicine and Pharmacy, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0002-9997-6390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic plasma exchange is a second-line therapy for severe hyperthyroidism when anti-thyroid drugs (ATD) are contraindicated or ineffective. We report five patients (three males, two females, age range: 30-70 years old): ATD-induced agranulocytosis (n = 2); ATD-induced cholestatic hepatitis (n = 1); refractory hyperthyroidism with large goiter (n = 1); thyroid storm during pregnancy (n = 1). A total of six TPE sessions were performed (five with fresh frozen plasma, one with 5% albumin). Among sessions with quantifiable baseline fT4, levels decreased by a mean of 39.0% per session; two sessions had baseline fT4 above the assay's upper limit of quantification, precluding exact calculation, though both showed reductions of at least 50%. Four patients underwent successful thyroidectomy; one continued medical management. No intraoperative thyroid storms occurred. TPE could be an effective bridging strategy for patients with severe hyperthyroidism and ATD intolerance.

Indexed as

HyperthyroidismPlasma ExchangeAdultAgedAgranulocytosisAntithyroid AgentsFemaleHumansMaleMiddle AgedPregnancyThyroid CrisisThyroidectomyThyroxineAntithyroid AgentsThyroxineagranulocytosishepatotoxicityhyperthyroidismtherapeutic plasma exchangethyroid storm

Identifiers

PMID42604987
PMCPMC13478353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.