Evidence map›Paper›PMID 42604562›Full record

ArticleVirulence2026

Rotavirus-NSP5 interacts with and hijacks host ATP citrate lyase to viroplasms, enhancing lipid biosynthesis for facilitating rotavirus infection.

Ranjana Sharma, Shreya Banerjee, Ratul Datta Chaudhuri, Kaushik Kumar Dey, Animesh Gope, Shin-Ichi Miyoshi, Daisuke Imamura, Mamta Chawla-Sarkar

Abstract read
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ranjana SharmaRegional VRDL, ICMR- National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India.
Shreya BanerjeeRegional VRDL, ICMR- National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India.
Ratul Datta ChaudhuriRegional VRDL, ICMR- National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India.
Kaushik Kumar DeyDivision of Applied Biosciences, ICMR- National Institute for Research in Bacterial Infections (Formerly ICMR-NICED), Kolkata, India.
Animesh GopeDepartment of Central Instrumental Facility, ICMR- National Institute for Research in Bacterial Infections (Formerly ICMR-NICED), Kolkata, India.
Shin-Ichi MiyoshiICMR- National Institute for Research in Bacterial Infections (Formerly ICMR-NICED), Collaborative Research Center of Okayama University for Infectious Diseases in India, Kolkata, India.
Daisuke ImamuraICMR- National Institute for Research in Bacterial Infections (Formerly ICMR-NICED), Collaborative Research Center of Okayama University for Infectious Diseases in India, Kolkata, India.
Mamta Chawla-SarkarRegional VRDL, ICMR- National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India.ORCID 0000-0002-7141-1785

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus (RV) replication occurs within viroplasms (VMs) and is initiated by two RV non-structural proteins NSP2 and NSP5. Viruses exploit host cellular components for their replication and assembly; however, information on the roles of host proteins in VM dynamics and RV replication is limited. Thus, in the current study, we used proteomics to identify host proteins that interact with NSP5 during RV infection to delineate their role in virus replication. A large number of host proteins (

Indexed as

ATP Citrate (pro-S)-LyaseHost-Pathogen InteractionsLipidsRNA-Binding ProteinsRotavirusRotavirus InfectionsViral Nonstructural ProteinsAnimalsCell LineHumansMicePhosphorylationProteomicsVirus ReplicationATP Citrate (pro-S)-LyaseLipidsNS35 protein, rotavirusRNA-Binding ProteinsViral Nonstructural ProteinsATP citrate lyasehost-pathogen interactionnon-structural protein 5 (NSP5)proteomicsRotavirusviroplasm

Identifiers

PMID42604562
PMCPMC13483473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.