Evidence map›Paper›PMID 42604407›Full record

ArticleCureus2026

Pseudoinvasive Colon Cancer Mimicking Invasive Colon Cancer: A Case Report.

Masaya Tsubakiyama, Shoji Oura, Katsuji Tokuhara

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Masaya TsubakiyamaDepartment of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.
Shoji OuraDepartment of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.
Katsuji TokuharaDepartment of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudoinvasion refers to a condition that resembles invasive cancer despite being either a non-invasive cancer or a benign disorder. We experienced a case of non-invasive colon cancer mimicking invasive colon cancer. An 82-year-old man without any surgical or endoscopic intervention to the descending colon had a descending colon polyp, which showed Japan Narrow Band Imaging Expert Team (JNET) category type 2A. However, it was large and highly elevated, had a contracted fold, and felt tense, leading to the tentative evaluation of invasive colon cancer, though lacking full endoscopic evaluation of the mass surface due to incomplete removal of mucus. Positron emission tomography (PET), however, showed no fluorodeoxyglucose uptake in the mass. We operated on the patient with a left hemicolectomy and lymph node dissection after the pathological diagnosis of well-differentiated adenocarcinoma. Postoperative pathological study showed no lymph node metastasis, non-invasive well-differentiated adenocarcinoma cells growing in a tubular fashion, and non-invasive cancer cells growing in an inverted fashion with cystic components under the non-invasive well-differentiated adenocarcinoma cells, leading to the final evaluation of pseudoinvasion. The patient recovered uneventfully, was discharged on the eighth day after surgery, and has been well for 13 months. Endoscopic specialists should take the pseudoinvasion into consideration and perform endoscopic ultrasound evaluation when noticing discrepancies among narrow band image findings, PET findings, and pathological findings of endoscopic biopsies to avoid over-treatment for non-invasive colon cancer with pseudoinvasion.

Indexed as

cystic componentsno fluorodeoxyglucose uptakenon-invasive colon cancerpetpseudoinvasion

Identifiers

PMID42604407
PMCPMC13477411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.