ArticleJTCVS open2026
Early experience using quantitative guidelines for aortic valve repair in pediatric patients.
Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Simulation-guided outlet valve repair: early integration of computationally-derived principles of free-edge length in bicuspidization repair.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Objective: Pediatric aortic valve repair has traditionally been guided by qualitative assessment. In this study, we present our early experience using quantitative guidelines to inform repair. Methods: We present a simple model of normal aortic valve proportions and compare outcomes of valves repaired with and without model-based guidelines. In a secondary analysis of a subset of valves that preoperatively exhibited 2 or 3 distinct leaflets with normal commissures, we assess whether achieving target normal leaflet free edge lengths is associated with less regurgitation. Results: Valve repair aided by modeling exhibited similar rates of aortic regurgitation (AR) and aortic stenosis (AS) on discharge and follow-up echocardiograms to controls. The repair versus replacement rate increased significantly from 57% in controls to 71% during the period in which modeling was used ( Conclusions: Use of quantitative repair guidelines achieved similar outcomes and higher repair rates despite higher preoperative valve complexity. Among valves with distinct leaflets and normal commissures, changes in AR from preoperation to postoperation closely tracked surgical changes to relative leaflet free edge length. Although initial results are promising, larger numbers and longer follow-up are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.