ArticleJTCVS open2026
Natural history and clinical outcomes of de novo functional tricuspid regurgitation after the Ross procedure.
Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Objective: To characterize the natural history, predictors, and clinical outcomes of de novo severe functional tricuspid regurgitation (TR) following the Ross procedure. Methods: At a single institution, 699 consecutive adults without preoperative severe TR undergoing the Ross procedure between 2011 and 2025 were reviewed. De novo severe TR was defined as TR grade ≥3 within 6 months postoperatively. Propensity score overlap weighting was used to balance 21 covariates between patients who developed de novo severe TR and those who did not. Weighted generalized estimating equations were used to analyze longitudinal TR trajectories. Predictors were identified using LASSO regression. Survival and reintervention were compared using weighted Kaplan-Meier and Aalen-Johansen methods. Results: De novo severe TR occurred in 61 patients (8.7%), appearing at a median of 5 days postoperatively. The groups demonstrated significantly different TR trajectories ( Conclusions: De novo severe TR after the Ross procedure is common but transient, resolving spontaneously without any adverse impact on survival or need for reintervention. These findings support a conservative management strategy with echocardiographic surveillance.
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