Evidence map›Paper›PMID 42604342›Full record

ArticleJTCVS open2026

Immediate postoperative biomarkers characterize severity of primary graft dysfunction after heart transplantation.

Shreyas Kiran, Phoebe Miller, Isha Maniyar, Jashdeep Dhillon, Sarah Sullivan, Andrew Akcelik, Amy G Fiedler, Jason Smith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shreyas KiranSchool of Medicine, University of California San Francisco, San Francisco, Calif.
Phoebe MillerDepartment of Surgery, University of California San Francisco, San Francisco, Calif.
Isha ManiyarSchool of Medicine, University of California San Francisco, San Francisco, Calif.
Jashdeep DhillonSchool of Medicine, University of California San Francisco, San Francisco, Calif.
Sarah SullivanDepartment of Surgery, University of California San Francisco, San Francisco, Calif.
Andrew AkcelikDepartment of Cardiothoracic Surgery, University of California San Francisco, San Francisco, Calif.
Amy G FiedlerDepartment of Cardiothoracic Surgery, University of California San Francisco, San Francisco, Calif.
Jason SmithDepartment of Cardiothoracic Surgery, University of California San Francisco, San Francisco, Calif.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Primary graft dysfunction (PGD) remains the leading cause of early morbidity and mortality after orthotopic heart transplantation. Postoperative lactate and the venoarterial carbon dioxide gap (Pv-a CO Methods: We performed a single-center retrospective study of adult recipients of orthotopic heart transplantation (May 2020 to May 2023). PGD was defined according to International Society for Heart and Lung Transplantation criteria and categorized as none, moderate, or severe. Pv-a CO Results: Among 110 recipients, PGD occurred in 50 (45%) cases, including 39 moderate and 11 severe. At T0, both biomarkers demonstrated stepwise increases with PGD severity. Each 1-mm Hg increase in Pv-a CO Conclusions: Immediate posttransplant Pv-a CO

Indexed as

biomarkersblood lactateheart transplantationhemodynamicspostoperative complicationsprimary graft dysfunctionvenoarterial carbon dioxide gap

Identifiers

PMID42604342
PMCPMC13477142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.