Trial reportJTCVS open2026
Intercostal nerve block with liposomal bupivacaine versus no regional analgesia after uniportal thoracoscopic surgery: A randomized controlled trial.
Trial report in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To evaluate intercostal nerve block (administered with liposomal bupivacaine) compared with no regional analgesia after video-assisted thoracoscopic surgery lung resection. Methods: In this randomized controlled trial, patients undergoing video-assisted thoracoscopic surgery were randomly assigned 1:1 to receive intercostal nerve block using liposomal bupivacaine or standard care without regional analgesia (control). The primary end point was resting pain at 24 hours postoperatively. Secondary outcomes included cumulative resting pain over 72 hours, opioid consumption in morphine milligram equivalents (MME), Total Quality of Recovery-15 scores, length of stay, and adverse events. Results: A total of 199 patients were included (intervention, n = 100; control, n = 99). Median resting pain at 24 hours was lower with intercostal nerve block using liposomal bupivacaine than with control (2.0 [interquartile range, 1.0-3.0] vs 3.0 [interquartile range, 3.0-4.0]; Conclusions: Compared with no regional analgesia, intercostal nerve block with liposomal bupivacaine reduced resting pain at 24 hours after video-assisted thoracoscopic surgery lung resection and was associated with lower opioid consumption and improved early recovery. However, this study cannot confirm its superiority over standard bupivacaine or other regional blocks.
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