ArticleJTCVS open2026
Survival and outcomes of coronary artery bypass grafting in patients with extremely low ejection fraction (≤20%): A systematic review and meta-analysis.
Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Objectives: To assess perioperative outcomes and long-term survival of coronary artery bypass in patients with ejection fraction (EF) 20% or less. Methods: We performed a systematic search of MEDLINE, EMBASE, and CENTRAL via OVID for both randomized controlled trials and cohort studies involving patients with EF ≤20% undergoing coronary artery bypass grafting, including results from 1995 to December 2023. Random-effects prevalence meta-analysis was performed using the meta library in R. Outcome prevalence was logit-transformed and pooled using a generalized linear mixed-effects model. The presence of heterogeneity was assessed using the Cochran Q test with a significance of Results: A total of 29 studies involving 5910 patients were included in this analysis. The pooled prevalence of perioperative mortality was 9%. Postoperative myocardial infarction and stroke prevalence were 2% and 3%, respectively. Low cardiac output syndrome definition varied across studies, and its pooled prevalence was 16%, with postoperative mechanical circulatory support requirement at 9%, the pooled 5-year survival rate was 74%. Conclusions: Despite elevated short-term risk, patients with severely low LVEF (≤20%) may derive long-term survival benefit from coronary artery bypass grafting and therefore it should remain a consideration in advanced heart failure therapies.
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