Evidence map›Paper›PMID 42604273›Full record

ArticleStructural heart : the journal of the Heart Team2026

Prediction of Underexpansion Following Transcatheter Aortic Valve Implantation and Efficacy of Balloon Postdilatation.

Mariama Akodad, Sri Krishna Sivakumar, Joshua Yoon, Courtney Ream, David A Wood, Jonathon A Leipsic, Philipp Blanke, John G Webb, Lakshmi Prasad Dasi, David Meier and 1 more

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Article in Structural heart : the journal of the Heart Team, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mariama AkodadRamsay Santé, Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques-Cartier, Massy, France.
Sri Krishna SivakumarDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Joshua YoonCardiovascular Translational Laboratory, Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital & Providence Research, Vancouver, Canada.
Courtney ReamDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
David A WoodCentre for Heart Valve Innovation, St. Paul's Hospital, Vancouver, Canada.
Jonathon A LeipsicCentre for Heart Valve Innovation, St. Paul's Hospital, Vancouver, Canada.
Philipp BlankeCentre for Heart Valve Innovation, St. Paul's Hospital, Vancouver, Canada.
John G WebbCentre for Heart Valve Innovation, St. Paul's Hospital, Vancouver, Canada.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
David MeierCardiovascular Translational Laboratory, Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital & Providence Research, Vancouver, Canada.
Stephanie L SellersCardiovascular Translational Laboratory, Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital & Providence Research, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter heart valve (THV) underexpansion following transcatheter aortic valve implantation (TAVI) is associated with elevated gradients, paravalvular leak, and/or risk of hypoattenuating leaflet thickening. We aimed to simulate TAVI using pre-TAVI computed tomography (CT) images to predict the extent of THV underexpansion and the effect of staged balloon postdilatation on THV expansion. Methods: Patients who underwent balloon postdilatation as a staged procedure for symptomatic THV dysfunction following native or valve-in-valve TAVI with available pre-TAVI, post-TAVI, and post-balloon aortic valvuloplasty CT between 2016 and 2023 were analyzed. TAVI and postdilatation were simulated computationally in patient-specific models using finite element analysis. Simulations were performed in blinded fashion without information of index procedure. THV expansion was defined as the percentage of THV area achieved by THV in CT or modeling when compared to nominal area defined by THV manufacturer. Results: Among patients with balloon-expandable THVs following TAVI, the differences in expansion between CT and simulation measurements were -0.88% ± 3.27% ( Conclusions: Patient-specific computational modeling can predict THV underexpansion during the index procedure and the effect of postdilatation on THV expansion.

Indexed as

Computational modelingPostdilatation balloonTranscatheter aortic valve implantationTranscatheter heart valve dysfunction

Identifiers

PMID42604273
PMCPMC13476896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.