Evidence map›Paper›PMID 42604197›Full record

ArticleJTCVS open2026

Paying the toll: Transfusion and outcomes of patients bridged with mechanical circulatory support to heart transplantation.

Swaroop Bommareddi, Chen Chia Wang, Walter Navid, Esha Chawla, John Trahanas, Brian Lima, Awab Ahmad, Kevin C McGann, Mark Petrovic, Stephen Devries and 7 more

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Swaroop BommareddiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Chen Chia WangVanderbilt University School of Medicine, Nashville, Tenn.
Walter NavidVanderbilt University School of Medicine, Nashville, Tenn.
Esha ChawlaVanderbilt University School of Medicine, Nashville, Tenn.
John TrahanasDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Brian LimaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Awab AhmadDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Kevin C McGannDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Mark PetrovicVanderbilt University School of Medicine, Nashville, Tenn.
Stephen DevriesDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Joshua LowmanDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Tarek AbsiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Eric QuintanaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Kelly SchlendorfDivision of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Matthew BacchettaDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Ashish S ShahDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
Aaron M WilliamsDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tenn.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
NCATS NIH HHS UL1 TR000445
6 · The paper itself

Abstract

Objective: Various mechanical circulatory support (MCS) strategies exist to bridge patients with heart failure to heart transplant. This study provides a comprehensive analysis comparing perioperative transfusion requirements and posttransplant outcomes between recipients with various pretransplant MCS types. Methods: All adult heart transplants from January 2020 to June 2025 from a single-center, minus multiorgan transplants or adult congenital heart disease cases, were included. Patients were stratified as: no MCS, pretransplant intra-aortic balloon pump (IABP), Impella, durable left ventricular assist device (LVAD), and extracorporeal membrane oxygenation (ECMO). Results: A total of 600 adult heart transplants were included, of which 263 (43.8%) had no MCS, 91 (15.2%) an IABP, 47 (7.8%) an Impella, 179 (29.8%) a durable LVAD, and 20 (3.3%) had ECMO as pretransplant support. Intraoperative transfusion requirements were greater in the Impella, LVAD, and ECMO cohorts compared with the no-MCS cohort. Postoperatively, both LVAD and ECMO groups had greater transfusions relative to those without MCS. Transfusion requirements were similar between the LVAD and ECMO cohorts. The IABP, Impella, and LVAD groups had comparable posttransplant outcomes relative to the no-MCS group. The ECMO cohort had greater 30-day and 1-year mortality rates compared with those without pretransplant MCS. Conclusions: Perioperative transfusion requirements were comparable between those with no pretransplant MCS and those with IABP or Impella and was greater in those with pretransplant LVAD or ECMO. Survival in patients with IABP, Impella, and LVAD was similar to those with no MCS and worse in patients with ECMO compared with no MCS.

Indexed as

bridge to transplantheart transplantmechanical circulatory supporttransfusions

Identifiers

PMID42604197
PMCPMC13477139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.