Evidence map›Paper›PMID 42604157›Full record

ArticleJTCVS open2026

Hemostatic therapies and ambiguous abnormal bleeding in cardiac operating rooms: A real-world, case-based evaluation of clinical practices.

Alexandre Sebestyen, Alexandre Behouche, Jean-Noël Evain, Julien Picard, Olivier Chavanon, Pierre Albaladejo

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandre SebestyenDepartment of Cardiac Surgery, Grenoble Alpes University Hospital, Grenoble, France.
Alexandre BehoucheAlps Research Assessment and Simulation Centre, Grenoble Alpes University, Grenoble, France.
Jean-Noël EvainAlps Research Assessment and Simulation Centre, Grenoble Alpes University, Grenoble, France.
Julien PicardAlps Research Assessment and Simulation Centre, Grenoble Alpes University, Grenoble, France.
Olivier ChavanonDepartment of Cardiac Surgery, Grenoble Alpes University Hospital, Grenoble, France.
Pierre AlbaladejoAlps Research Assessment and Simulation Centre, Grenoble Alpes University, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Hemostatic therapy is commonly used in cardiac surgery. Despite tools to reduce inappropriate use, variability remains, mainly due to a lack of standards, especially intraoperatively. This study examined practices in cardiac operating rooms using a standardized clinical case. Methods: French cardiac anesthesiologists and surgeons responded to a nationwide questionnaire, including a multiple-choice test based on a clinical case of ambiguous bleeding despite normal tests. The use of hemostatic therapies during surgery-reversal, chest closure, and transfer-was assessed with a fictitious surgeon or anesthesiologist involved in the assessment. Interrater reliability was measured using Gwet's AC1, and ratings before and after the intervention were compared with a paired Fisher exact test. Nonclinical factors and perceptions of bleeding were evaluated using a Likert scale. Results: Interrater reliability was poor among 73 anesthesiologists (γ = 0.38 [95% confidence interval, 0.03 to 0.73]) and 31 surgeons (γ = 0.16 [95% confidence interval, -0.31 to 0.63]). Users' rates significantly increased since chest closure, mainly after the fictitious colleague intervention, regardless of profession (from 29.0% to 89.3% [ Conclusions: Hemostatic therapy may require standardization to better manage intraoperative bleeding. Teamwork, especially with surgeons, is vital for shared awareness in these complex situations.

Indexed as

cardiac surgerycase-based simulationintraoperative hemorrhagepatient blood managementsituational awareness

Identifiers

PMID42604157
PMCPMC13477111

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.