Evidence map›Paper›PMID 42604002›Full record

ArticleJournal of translational autoimmunity2026

SARS-CoV-2-induced IgG repertoires shape T cell responses, microRNA regulation, and autoreactivity according to disease severity.

Fabio da Ressureição Sgnotto, Nicolle Rakanidis Machado, Lais Alves do Nascimento, Beatriz Oliveira Fagundes, Isabella Siuffi Bergamasco, Sabri Saeed Sanabani, Maria Notomi Sato, Jefferson Russo Victor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational autoimmunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabio da Ressureição SgnottoPost Graduation Program in Health Sciences, Santo Amaro University (UNISA), São Paulo, Brazil.
Nicolle Rakanidis MachadoLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Lais Alves do NascimentoLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Beatriz Oliveira FagundesDepartment of Dermatology, University Medical Center Groningen, Groningen, the Netherlands.
Isabella Siuffi BergamascoPost Graduation Program in Health Sciences, Santo Amaro University (UNISA), São Paulo, Brazil.
Sabri Saeed SanabaniLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Maria Notomi SatoLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Jefferson Russo VictorPost Graduation Program in Health Sciences, Santo Amaro University (UNISA), São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 infection can generate IgG repertoires with functions beyond viral neutralization. We purified IgG from non-exposed healthy controls, moderate and severe COVID-19 patients, and IVIg, and assessed their effects on healthy-donor PBMCs. COVID-19 IgG bound CD4

Indexed as

AutoreactivityCD4+ T cellsCD8+ T cellsCOVID-19CytokinesDisease severityIgG repertoireImmune modulationmicroRNAsSARS-CoV-2

Identifiers

PMID42604002
PMCPMC13476528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.