Evidence map›Paper›PMID 42603982›Full record

ArticleSynthetic and systems biotechnology2027

Alternative splicing-induced thioesterase domain deficiency drives the production of natural orsellinic acid derivatives with a pantetheine moiety in nonreducing polyketide synthases.

Qingpei Liu, Liwei Zhou, Yifu Gong, Xinqiong Liu, Jiajie Ma, Wei Liu, Haiyan Fu, Xiaolong Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qingpei LiuSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Liwei ZhouSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Yifu GongSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Xinqiong LiuCollege of Life Science, South-Central Minzu University, Wuhan, 430074, PR China.
Jiajie MaSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Wei LiuSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Haiyan FuSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.
Xiaolong YangSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonreducing polyketide synthase Preu6 catalyzes didepside formation by interaction of starter acyl transferase and thioesterase (TE) domains. Here, we show that an aberrant transcript,

Indexed as

Alternative splicingNatural productsOrsellinic acid derivativesPantetheinePolyketide synthasesThioesterase domain

Identifiers

PMID42603982
PMCPMC13476535

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.