ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026
Impact of Optical Coherence Tomography Scan Pattern and Chorio-Scleral Interface Delineation on Choroidal Vascularity Index Measurements.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo compare radial and horizontal raster acquisition patterns using spectral-domain optical coherence tomography (OCT) for assessing choroidal vascularity index (CVI) in healthy eyes and to evaluate how variability in chorio-scleral interface (CSI) delineation influences CVI measurements.
methodsOCT images of 25 eyes from 25 healthy adults were acquired using 12-line radial and 31-line horizontal raster scans with enhanced depth imaging. CVI was measured manually using three different posterior boundaries-defined as the upper (vascular), middle (vascular-stromal) and lower (stromal) CSI boundaries. Agreement between CSI boundaries and scan patterns was assessed using Bland-Altman analysis. Topographical CVI variations across 6-mm Early Treatment of Diabetic Retinopathy Study (ETDRS) subfields, quadrants and rings were evaluated using two-way repeated-measures ANOVA.
resultsParticipants were aged 21-31 years (72% female; mean spherical equivalent -2.97 ± 2.02 D). Mean CVI differences ranged from 1.43 to 2.38% between the upper and middle CSI boundaries and from 1.23 to 2.04% between the middle and lower CSI boundaries. Comparisons between the upper and lower CSI boundaries resulted in larger CVI differences, ranging from 2.90 to 4.42%. The coefficient of variation for CVI was low (<2%) between radial and raster scan patterns, and Bland-Altman analysis showed overall good agreement. The 31-line raster scan measured 0.51% higher CVI in the central foveal region, whereas the 12-line radial scan yielded 0.64-1.10% higher CVI in the perifoveal region. Significant mean differences were observed only in the outer temporal subfield (-1.10%, p = 0.005) and outer ring (-0.77%, p = 0.02). No significant scan-pattern effect was found, but CVI varied significantly across the ETDRS grid, with the lowest values in the outer nasal subfield, nasal quadrant and outer ring.
conclusionsRadial scans provide CVI measurements comparable to raster scans, with faster acquisition, supporting practical use in children. Standardising CSI delineation is crucial for consistent CVI comparisons across studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.