ArticleSpinal cord series and cases2026
Skin and tissue changes after spinal cord injury-A scoping review.
Article in Spinal cord series and cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Skin and tissue changes after spinal cord injury-A scoping review.Spinal cord series and cases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designScoping review.
objectivesSpinal cord injury causes complex and severe changes in affected skin and underlying tissues, increasing the risk of pressure ulcer development and impeding wound healing. This scoping review provides an updated overview on skin and tissue changes after spinal cord injury. Given the complexity and inconsistent evidence of the topic, this review outlines current knowledge and highlights research gaps.
methodsA comprehensive literature search was conducted in Medline, Embase, Cochrane Library, and SCOPUS databases. Studies written in English addressing skin and tissue changes after spinal cord injury were included, with no restrictions on study type or publication year. Two reviewers independently screened the studies, and eligible articles were organized into the following six subgroups: 1) histopathology, 2) ultrasonography, 3) biomechanical properties, 4) skin perfusion, 5) sebum- and sweat gland excretion, and 6) microbiota.
resultsOut of 5387 articles screened, twenty-three met the inclusion criteria. Findings revealed epidermal atrophy characterized by progressive thinning over time, while the dermal layer demonstrated fibrosis and reduced collagen synthesis. Results on skin thickness were inconsistent, though increased tissue stiffness was consistently reported. Skin perfusion was compromised, with diminished reactive hyperemia, impaired vascular autoregulation, and reduced spontaneous skin oxygenation.
conclusionSkin and tissue affected by spinal cord injury exhibit compromised quality with characteristics of aged and injured skin. Consequently, the skin is less able to resist pressure, shear stress, and ischemia. The reviewed literature reveals substantial gaps in knowledge, underscoring the need for further research to improve clinical care and management.
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