Evidence map›Paper›PMID 42603389›Full record

ReviewSleep medicine reviews2026

Adverse experiences in childhood and adolescence in relation to sleep health in adulthood: An overview of systematic reviews and a global evidence map.

Symielle A Gaston, Wensu Zhou, Rupsha Singh, Tracy C Shields, Alicia A Livinski, Susan Redline, Jean-Philippe Chaput, Karen Spruyt, Fang Han, Judith Owens and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sleep medicine reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Symielle A GastonEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Wensu ZhouEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Rupsha SinghEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Tracy C ShieldsNational Institutes of Health Library, Office of Research Services, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Alicia A LivinskiNational Institutes of Health Library, Office of Research Services, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Susan RedlineDepartment of Medicine, Harvard Medical School, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Jean-Philippe ChaputHealthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; Department of Pediatrics, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Karen SpruytUniversité de Paris, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.
Fang HanDivision of Sleep Medicine, Peking University People's Hospital, and PKU-IDG/McGovern Institute for Brain Research, Beijing, China.
Judith OwensBoston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Chandra L JacksonEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA; Division of Intramural Research, National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA. Electronic address: Chandra.Jackson@nih.gov.
World Sleep Society Global Adolescent Sleep Project Taskforce

Funding

Social and Environmental Determinants of Health EquityZIAES103325 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JACKSON, CHANDRA · 2017 to 2025
$12.7M
Intramural NIH HHS ZIA ES103325
6 · The paper itself

Abstract

Adversities in childhood and adolescence (ACA) can disrupt biological, developmental, and behavioral processes, potentially contributing to poorer sleep in adulthood. However, the certainty of the evidence of this association remains unclear. To synthesize and evaluate evidence of associations between ACA and adult sleep health (≥18 years) across World Health Organization regions while considering benevolent and risk factors, we conducted an overview of systematic reviews/meta-analyses. Using a predefined protocol, we systematically reviewed records published from database (n = 5) inception to February 2026, synthesized results, and performed quality and bias appraisal using validated tools, which allowed for assessment of the overall certainty of evidence. Twelve systematic reviews, including one relevant meta-analysis, were identified. ACA exposure was consistently associated with poorer sleep (e.g., insomnia symptoms, nightmares, higher arousals) in adulthood. Confidence in findings was generally critically low, and risk of bias was high, resulting in low certainty, overall. Evidence was concentrated in Regions of the Americas and Europe, with no representation from low-income countries. Reviews broadly summarized ACA-sleep associations, limiting synthesis of potential moderation by benevolent and risk factors. ACAs appear associated with poorer sleep health in adulthood; however, certainty remains low. More research across global populations is needed.

Indexed as

AdultsAdverse childhood experiencesChildhood traumaSleep

Identifiers

PMID42603389
PMCPMC13523066

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.