Evidence map›Paper›PMID 42603283›Full record

ArticleChemistry & biodiversity2026

In Vitro and In Vivo Evaluation of the Antidiabetic, Antioxidant, and Antibacterial Activities of the Hydroethanolic Extract of Dysphania ambrosioides L.

Fahd Kandsi, Fatima Zahra Lafdil, Saliha Bouknana, Naoufal El Hachlafi, Mohamed Jeddi, Raffaele Conte, Mohamed Bnouham, Kaoutar Fikri-Benbrahim, Nadia Gseyra

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Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fahd KandsiLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.ORCID https://orcid.org/0000-0003-2696-1734
Fatima Zahra LafdilLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Saliha BouknanaLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.ORCID https://orcid.org/0000-0002-9088-0122
Naoufal El HachlafiLaboratory of Microbial Biotechnology and Bioactive Molecules, Faculty of Sciences and Technologies, Sidi Mohamed Ben Abdellah University, Fez, Morocco.ORCID https://orcid.org/0000-0003-0768-5914
Mohamed JeddiLaboratory of Microbial Biotechnology and Bioactive Molecules, Faculty of Sciences and Technologies, Sidi Mohamed Ben Abdellah University, Fez, Morocco.ORCID https://orcid.org/0000-0002-7165-1842
Raffaele ConteResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Naples, Italy.
Mohamed BnouhamLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.ORCID https://orcid.org/0000-0001-9473-1290
Kaoutar Fikri-BenbrahimLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.ORCID https://orcid.org/0000-0002-2923-9299
Nadia GseyraLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysphania ambrosioides L. (Amaranthaceae) is a medicinal plant widely used in traditional Moroccan medicine for the management of diabetes-related disorders. This study investigated the antidiabetic, antioxidant, and antibacterial activities of its hydroethanolic extract. Antidiabetic potential was evaluated through pancreatic α-amylase inhibition (in vitro and in vivo) and intestinal glucose absorption (in situ). Antioxidant and antibacterial activities were assessed using standard chemical assays and selected bacterial strains. The extract showed significant inhibition of pancreatic α-amylase in vitro (IC

Indexed as

AmaranthaceaeAnti-Bacterial AgentsAntioxidantsDiabetes Mellitus, ExperimentalHypoglycemic AgentsPlant Extractsalpha-AmylasesAnimalsEscherichia coliEthanolMaleMicrobial Sensitivity TestsPseudomonas aeruginosaRatsRats, WistarStaphylococcus aureusalpha-AmylasesAnti-Bacterial AgentsAntioxidantsEthanolHypoglycemic AgentsPlant ExtractsantibacterialantidiabeticantioxidantDysphania ambrosioides L

Identifiers

PMID42603283
PMCPMC13477237

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.