Evidence map›Paper›PMID 42603116›Full record

ArticlePaediatric anaesthesia2026

Current Use, Monitoring and Reversal of Neuromuscular Block in Pediatric Anesthesia and Intensive Care: A Web-Based Cross-Sectional ESAIC Survey.

Giulia Bonatti, Mirjana Gander, Arash Afshari, Francis Veyckemans, Thomas Fuchs-Buder, Thomas Riva, Markus Huber, Nicola Disma, Alexander Fuchs

Abstract read
In one paragraph

Article in Paediatric anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Giulia BonattiUnit for Research in Anaesthesia, IRCCS Istituto Giannina Gaslini, Genoa, Italy.ORCID https://orcid.org/0000-0003-2290-7749
Mirjana GanderDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0009-0004-9319-0807
Arash AfshariDepartment of Paediatric and Obstetric Anaesthesia, Juliane Marie Centre, Rigshospitalet & Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-5117-9715
Francis VeyckemansUCLouvain Medical School, Brussels, Belgium.ORCID https://orcid.org/0000-0001-9670-8588
Thomas Fuchs-BuderUniversité de Lorraine, CHRU Nancy, Hôpital de Brabois, Nancy, France.ORCID https://orcid.org/0000-0002-8041-1234
Thomas RivaDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0003-1297-3427
Markus HuberDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-8081-0684
Nicola DismaUnit for Research in Anaesthesia, IRCCS Istituto Giannina Gaslini, Genoa, Italy.ORCID https://orcid.org/0000-0002-2960-9333
Alexander FuchsDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-7188-1683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuromuscular blocking agents are recommended by the European Society of Anaesthesiology and Intensive Care (ESAIC) and European Society of Paediatric Anaesthesia (ESPA) for facilitating tracheal intubation in children. Despite these recommendations, real-world data on how neuromuscular blocking agents are used, monitored, and reversed remain scarce.

aimsTo identify and characterize self-reported neuromuscular blocking agent practice patterns across European and non-European countries, in the period preceding publication of the joint ESAIC and ESPA guidelines.

methodsWe conducted an anonymous, cross-sectional survey between 12 November and 12 December 2025, targeting members of the ESAIC, ESPA, and the French and Spanish national pediatric anesthesiology societies involved in pediatric airway management across 43 countries.

resultsThe survey was accessed by 904 persons, and 874 responses were included in the analysis. Most participants were from Europe (83.5%) and worked in mixed pediatric anesthesia and intensive care settings (71.2%). Rocuronium was the most frequently used neuromuscular blocking agent for both routine tracheal intubation (68%; 95% CI 65%-71%) and rapid sequence intubation (67%; 95% CI 64%-70%). Neuromuscular blocking agents were used "always" or "mostly" before routine intubation in 47% of neonates (≤ 30 days) and 50% of infants (< 1 year), whereas "rarely" or "never" use was reported in 30% and 24%, respectively. Most respondents (56%) assessed adequacy of neuromuscular block using a fixed time interval after neuromuscular blocking agent administration. Reversal was administered "always" before extubation by 27% of respondents, while 9.3% reported "rarely" and 2.9% "never." Only half of participants used quantitative neuromuscular monitoring to guide reversal. Sugammadex was used by 47%.

conclusionsSelf-reported clinical practice regarding neuromuscular blocking agent use in pediatric patients remains heterogeneous. Children are frequently intubated without neuromuscular blocking agents and extubated without consistent reversal. Quantitative neuromuscular monitoring remains uncommon. These practice patterns raise concerns for patient safety.

Indexed as

Critical CareNeuromuscular BlockadeNeuromuscular Blocking AgentsPediatric AnesthesiaChildChild, PreschoolCross-Sectional StudiesEuropeFemaleHumansInternetIntubation, IntratrachealSurveys and QuestionnairesNeuromuscular Blocking Agentsneuromuscular blockneuromuscular monitoringpediatric anesthesiaresidual neuromuscular blockrocuroniumRSIsugammadexsurvey studyTOFtrain‐of‐four monitoring

Identifiers

PMID42603116
PMCPMC13639220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.