Evidence map›Paper›PMID 42603106›Full record

ArticleRisk analysis : an official publication of the Society for Risk Analysis2026

Hospital Capacity Pooling in Pandemics: Simulation-Based Mortality Impacts and Diversification Mechanisms.

Francois Daudelin, Harrison B Zeff, Gregory W Characklis

Abstract read
In one paragraph

Article in Risk analysis : an official publication of the Society for Risk Analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francois DaudelinInstitute for Risk Management and Insurance Innovation, University of North Carolina, Chapel Hill, NC, USA.ORCID https://orcid.org/0009-0008-7578-8484
Harrison B ZeffInstitute for Risk Management and Insurance Innovation, University of North Carolina, Chapel Hill, NC, USA.
Gregory W CharacklisInstitute for Risk Management and Insurance Innovation, University of North Carolina, Chapel Hill, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated healthcare strain during the COVID-19 pandemic increased patient mortality rates and prompted costly non-pharmaceutical interventions. This work examines how the size of a hospital's service population, which can be expanded by linking hospitals through patient transfer networks, influences healthcare strain through two diversification mechanisms: (i) volatility dampening, which reduces the volatility of demand for healthcare resources by aggregating uncorrelated individual patient needs, and (ii) epidemic phase averaging, which flattens demand peaks by aggregating patients from asynchronous local epidemics. Using facility-level intensive care unit (ICU) data across three COVID waves, we analyze how service population size affects the size of peaks in ICU occupancy, evaluate the two proposed mechanisms, and explore the health impacts of pooling through scenario simulations grounded in observed occupancy levels. We find that volatility dampening effects reduce variability in ICU occupancy at a rate proportional to the square root of population size, whereas the effectiveness of epidemic phase averaging is dependent on the transmission dynamics of the pathogen. Increasing service population size also reduces the frequency and magnitude of demand spikes, lowering the likelihood of costly short-term interventions and increasing demand predictability. In the winter 2020 wave, our simulations find that randomly constructed local pools (2-6 hospitals) reduce COVID ICU mortality by a median of 2%-7%, with reductions exceeding 6%-18% in the top decile of outcomes. These findings suggest that coordinated patient transfer strategies could meaningfully reduce mortality and costs during future pandemics.

Indexed as

COVID-19Hospital Bed CapacityPandemicsComputer SimulationHumansIntensive Care UnitsSARS-CoV-2COVID‐19epidemicshealthcare capacitypandemic preparednessresource allocation

Identifiers

PMID42603106
PMCPMC13476866

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.