Evidence map›Paper›PMID 42602907›Full record

ArticleBiochemistry and biophysics reports2026

TRPA1 deficiency alters brown adipose tissue proteome and thermogenic gene expression during cold exposure in mice.

Cristhian D Sua-Cespedes, Otoniel Gonçalves Lima, Letícia Menezes Vasconcelos, Giovanna Zanetti, Miriane Avelino da Silva, Maria Nathalia Moraes, Guilherme Gomes, William Tadeu Festuccia, Ana Maria L Castrucci, José Thalles Lacerda

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In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cristhian D Sua-CespedesDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Otoniel Gonçalves LimaDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Letícia Menezes VasconcelosDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Giovanna ZanettiDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Miriane Avelino da SilvaDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Maria Nathalia MoraesDepartamento de Ciências Biológicas, Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Brazil.
Guilherme GomesPredikta Science Solutions, São Paulo, Brazil.
William Tadeu FestucciaDepartment of Physiology and Biophysics, University of São Paulo, São Paulo, Brazil.
Ana Maria L CastrucciDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
José Thalles LacerdaDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TRPA1 channels function as cold sensors and have been implicated in energy metabolism. We investigated the impact of TRPA1 on thermoregulation.

Indexed as

Brown adipose tissueCold exposureMetabolismThermogenesisTRPA1 channel

Identifiers

PMID42602907
PMCPMC13475522

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.