Evidence map›Paper›PMID 42602741›Full record

ArticleIranian journal of otorhinolaryngology2026

Adjuvant Treatment Strategies for Acute Invasive Fungal Rhinosinusitis: An in Vitro Evaluation.

Ermia Mousavi Mohammadi, Mehdi Bakhshaee, Amir Ashkan Mousavi Mohammadi, Hossein Zarrinfar, Imaneh Roshanzamir, Abolfazl Zanghaei, Sahar Nikrooz

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In one paragraph

Article in Iranian journal of otorhinolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ermia Mousavi MohammadiDepartment of Otorhinolaryngology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehdi BakhshaeeDepartment of Otorhinolaryngology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Ashkan Mousavi MohammadiStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Hossein ZarrinfarAllergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Imaneh RoshanzamirDepartment of Otorhinolaryngology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolfazl ZanghaeiDepartment of Otorhinolaryngology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sahar NikroozStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute invasive fungal rhinosinusitis (AIFR) is a severe condition with high morbidity and mortality, despite established management protocols. Adjuvant therapies may improve disease control. This study aimed to investigate the Materials and Methods: Sinonasal tissue biopsies obtained during endoscopic sinus surgery (ESS) from patients with AIFR, fungal ball, or allergic fungal rhinosinusitis (AFRS) were collected. Biopsies were exposed to 0.25% AA or 1.5% HP for 10 minutes and subsequently cultured on Sabouraud dextrose agar. Untreated tissue portions served as controls. Fungal growth was assessed and identified using macroscopic and microscopic characteristics. Results: Of 48 collected samples, 10 did not grow in any culture medium and were excluded. Among the remaining 38 samples, AA inhibited fungal growth in 7 samples (18.5%), and HP inhibited growth in 3 samples (8%). The majority of isolates were Conclusion: Although AA and HP exhibited some antifungal activity

Indexed as

Acetic acidAcute invasive fungal rhinosinusitisAspergillusHydrogen peroxideMucorales

Identifiers

PMID42602741
PMCPMC13474592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.