Evidence map›Paper›PMID 42602740›Full record

ArticlePlastic and reconstructive surgery. Global open2026

Deep Inferior Epigastric Perforator Flap Reconstruction of Breast Necrobiosis Lipoidica.

Karim Saoud, Adam Boukind, Udita Chapagain, Suzanne Crumley, Rajaa Almourani, Terence M Myckatyn

Abstract readCase Reports
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karim SaoudFrom the Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO.
Adam BoukindFrom the Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO.
Udita ChapagainDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
Suzanne CrumleyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
Rajaa AlmouraniDivision of Endocrinology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Terence M MyckatynFrom the Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrobiosis lipoidica (NL) is a granulomatous disease presenting as plaques with potential for progression to chronic ulcerating lesions. Breast involvement of the disease is rare. There are currently no FDA-approved medical therapies, and surgical treatment is controversial due to concerns for disease recurrence. Limited historical cases of surgical management demonstrate success when excision is taken to deep fascia. No prior reconstruction of NL manifesting on the breast has been documented in the literature. In this report, we present a patient with isolated ulcerated NL of the right breast refractory to medical management who was treated with resection to deep fascia and free flap reconstruction utilizing a deep inferior epigastric perforator flap. The patient initially presented with right breast implant rupture and underwent implant removal. After a 7-month monitoring period without disease progression, the patient elected for resection of her right breast NL with reconstruction by deep inferior epigastric perforator flap. The diseased tissue of the right breast was resected down to pectoralis fascia and immediately reconstructed with a deep inferior epigastric perforator flap. Although her postoperative course was complicated by infection, she subsequently recovered well with no NL recurrence and viable flap reconstruction at 10 months postoperatively. The patient was satisfied with her aesthetic outcome. To our knowledge, this is the first report describing reconstruction of NL of the breast and demonstrates the feasibility of resection to deep fascia and coverage without disease recurrence in refractory cases of NL.

Identifiers

PMID42602740
PMCPMC13475922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.