ArticleJournal of oral microbiology2026
Combined oral and peripheral blood detection of
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Periodontal pathogens are associated with cardiovascular disease, but clinical evidence linking Porphyromonas gingivalis (Pg) detection with coronary heart disease (CHD) and gut microbiota features remains limited. This study evaluated associations between oral and peripheral blood Pg detection status, CHD prevalence and exploratory gut microbiota characteristics in participants undergoing coronary angiography (CAG). Materials and methods: This analytical cross-sectional study included 165 CAG participants, including 124 patients with CAG-confirmed CHD and 41 non-CHD controls. Oral and peripheral blood Pg were detected by TaqMan quantitative polymerase chain reaction. Modified Poisson regression with robust standard errors was used to estimate adjusted prevalence ratios (PRs). Gut microbiota profiles were assessed by 16S rRNA gene sequencing. Results: Oral Pg positivity was more frequent in CHD participants than in non-CHD controls and remained associated with CHD in the primary adjusted model (PR = 1.237, 95% CI 1.044-1.465). The oral+/blood+ group showed the strongest association with CHD prevalence (PR = 1.362, 95% CI 1.099-1.688). Five FDR-significant ASVs were enriched in oral Pg-positive participants, whereas predicted pathways were not significant after FDR correction. Conclusions: Oral Pg positivity, especially combined oral and peripheral blood Pg nucleic acid positivity, was associated with CHD prevalence in this CAG-defined cohort.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.