Evidence map›Paper›PMID 42602431›Full record

ReviewFrontiers in immunology2026

Biomarkers for myelin oligodendrocyte glycoprotein-associated disease: recent advances and future.

Qingying Zheng, Muzi Wen, Xinyi Zheng, Linxin Wen, Ruogu Cheng, Ye Gao, Chao Yuan, Pei Shang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qingying ZhengDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Muzi WenDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xinyi ZhengDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Linxin WenDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ruogu ChengDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ye GaoDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chao YuanDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Pei ShangDepartment of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MOGAD is a rare autoimmune encephalomyelitis that shares similar clinical manifestations with other central nervous system demyelinating diseases. However, they must be distinguished due to their distinct pathogenesis and treatment methods. Currently, the clinical diagnosis of MOGAD primarily relies on patients' clinical manifestations and imaging features, with biomarker application being relatively limited. Meanwhile, research on MOGAD biomarkers has advanced rapidly, with findings mainly focusing on imaging features, antibody titers, nerve cell markers, cytokines, and inflammatory cell ratios. These biomarkers can distinguish among various autoimmune with similar clinical manifestations and exhibit certain specificity. If these biomarker findings are applied to the clinical diagnosis of MOGAD, they could enhance diagnostic accuracy and support earlier and more accurate diagnosis, while providing a scientific basis for evaluating disease progression and prognosis. We discuss the biomarkers and emerging biomarkers of MOGAD, emphasizing the specific changes and aspects that may be applicable to clinical diagnosis and treatment.

Indexed as

BiomarkersMyelin-Oligodendrocyte GlycoproteinMyelin Oligodendrocyte Glycoprotein Antibody-Associated DiseaseAnimalsAutoantibodiesCytokinesHumansAutoantibodiesBiomarkersCytokinesMyelin-Oligodendrocyte Glycoproteinbiomarkerscytokinesinflammatory cell ratiosMOG-IgG antibodiesmyelin oligodendrocyte glycoprotein associated disease (MOGAD)

Identifiers

PMID42602431
PMCPMC13473919

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.