Evidence map›Paper›PMID 42602379›Full record

ArticleTherapeutic advances in infectious disease

Determinants of visceral leishmaniasis among patients admitted to selected public hospitals in Guji and Borena Zones, southern Oromia, Ethiopia: An unmatched case-control study.

Abera Siyum, Lina Yitayew, Gemechis Tuke, Alo Edin, Bekam Yambo, Anteneh Fikrie Tekola

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Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Abera SiyumEast Borena Zone Health Office, Nagele Borena, Ethiopia.ORCID https://orcid.org/0009-0005-0617-839X
Lina YitayewEast Borena Zone Health Office, Nagele Borena, Ethiopia.
Gemechis TukeSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Alo EdinSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Bekam YamboSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Anteneh Fikrie TekolaSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Visceral leishmaniasis (VL) remains a significant public health concern in East Africa, with an estimated 30,000 cases reported annually. Ethiopia is among the most affected countries in the region, with the southern part of the country bearing a substantial share of the disease burden. Despite the high endemicity of VL in these areas, evidence regarding the factors contributing to disease occurrence among at-risk populations remains limited. Objectives: This study aims to identify the determinants of visceral leishmaniasis among patients admitted to selected public hospitals in Guji and Borena Zones, Southern Oromia, Ethiopia, in 2022. Design: A facility-based unmatched case-control study was conducted from April 15 to June 15, 2022. Methods: The study was conducted among randomly selected 335 (67 cases and 268 controls) patients in Nagele Borena and Yabelo General Hospitals of Guji and Borena Zones from April 15 to June 15/2022. A pretested and structured face-to-face interviewer administered questionnaire and chart review were used to collect the data. Data was entered into Epi Data version 4.6.0 and exported to SPSS version 25.0 for analysis. Bi-variable and multi variable binary logistic regression model were used to identify the determinants of VL. Adjusted odds ratio with 95% Confidence level and p-value of <0.05 were used to declare statistically significant associations. Result: A total of 335 study participants comprising 67 cases and 268 controls were included, with an overall response rate of 100%. In this study, presence of a dog in the household (AOR=7.2; 95%CI:3.6-18.1), presence of acacia trees around the home (AOR = 8.3; 95% CI: 4.2-17.1), presence of domestic animals in the household (AOR = 6.8; 95% CI: 2.3-16.7), no formal education (AOR = 3.6; 95% CI: 1.1-12.2), and termite hill around the home (AOR = 3.2; 95% CI: 2.02-9.3) were significantly associated with VL. Conclusion and recommendation: Our study identified several determinants of VL, that no formal education, presence of dog in the household, termite hill around the home, presence of domestic animals in the household and acacia trees around the home. Therefore, strengthening community awareness and promoting environmental risk-reduction strategies, including minimizing exposure to domestic animals, termite hills, and acacia trees in close proximity to households, may help reduce the risk of visceral leishmaniasis in the study area.

Indexed as

Borena ZonedeterminantsEthiopiaGuji Zonevisceral leishmaniasis

Identifiers

PMID42602379
PMCPMC13473799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.