Evidence map›Paper›PMID 42602172›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Establishing humoral immunity to rabies in a person with multiple sclerosis through booster vaccination: A case report.

D Dinov, P Hardeman, J Tessier, P V Sguigna

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D DinovThe Department of Neurology, the University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0002-9430-8617
P HardemanThe Department of Neurology, the University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0001-6181-0339
J TessierDivision of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0002-4571-6024
P V SguignaThe Department of Neurology, the University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0003-1825-575X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is known that certain disease-modifying therapies for multiple sclerosis impair humoral immunity; however, data on the effect of therapies on humoral immunity with human diploid cell rabies vaccine is limited. Here we present a case of a 31-year-old male with multiple sclerosis on ofatumumab who had a bat of unknown rabies status fly into his hand. Despite completing the standard rabies vaccination series per the World Health Organization recommendations, he did not establish humoral immunity until he received two additional booster vaccinations. This case highlights novel aspects of humoral immunity to rabies in a person taking ofatumumab.

Indexed as

humoral immune responsemultiple sclerosisofatumumabrabiesvaccine

Identifiers

PMID42602172
PMCPMC13473783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.