ArticleFrontiers in pediatrics2026
Body mass index, lung function, and FeNO in children with positive bronchodilator response: a cross-sectional study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the association between body mass index (BMI) and pulmonary function in pediatric outpatients with positive bronchodilator response. We hypothesized that BMI is associated with impaired pulmonary function in this population. Methods: This cross-sectional study was conducted at the Department of Pediatrics of Mianyang Central Hospital from January 2024 to December 2024. A total of 430 children aged 4-14 years who met the inclusion criteria were enrolled. Based on body mass index (BMI), participants were categorized into an higher BMI group ( Results: No significant differences were observed in baseline pulmonary function parameters, including FVC% predicted, FEV Conclusion: No significant differences were observed in baseline pulmonary function parameters across BMI groups in children aged 4-14 years. However, differences in bronchodilator-induced changes in FVC were identified among different BMI categories, and FeNO levels were positively associated with bronchodilator-induced changes in FVC. These findings indicate that body mass index and FeNO are independently associated with bronchodilator-related changes in lung function in this population, which may be relevant when interpreting pediatric pulmonary function test results.
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