ArticleFrontiers in cardiovascular medicine2026
Longitudinal associations between positive psychological factors and cardiovascular health.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: The health promoting effects of positive psychological factors in cardiovascular disease (CVD) are gaining increasing attention. Key factors such as optimism, mindfulness, positive affect, and life satisfaction have been linked to a lower incidence of CVD. While these effects are often explained by favorable health behaviors, potential biological mechanisms are insufficiently explored. Objectives: We aimed to to investigate independent associations between positive psychological factors and prospective changes in intermediate biological coronary heart disease (CHD) risk factors in CHD-patients, hypertensives (HT), and normotensive controls (NT). Methods: At baseline, 200 men (CHD=86,HT = 61,NT = 53) completed questionnaires on positive psychological factors and had blood samples collected. As CHD-risk factors lipid profiles (TC/HDL-ratio), blood glucose (HbA1c), coagulation (fibrinogen, D-dimer), and inflammation markers (CRP, IL-6, TNF-α) were measured. At 3-year follow-up, blood sample were collected from 126 men (NT = 34,HT = 37,CHD=55). Results: At baseline, the groups differed in positive affect only [F(2,197) = 3.63, Conclusion: Positive affect and life-satisfaction may benefit cardiovascular health by favorably affecting coagulation and inflammation, with potential implications for CHD prevention and intervention strategies.
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