Evidence map›Paper›PMID 42602110›Full record

ReviewFrontiers in cell and developmental biology2026

Ion channels and cardiac disease: mechanisms and functions of a disintegrin and metalloproteases and their substrates.

Yaru Liu, Linhui Xia, Xiangyu Wang, Wenxuan Wang, Huizhu Yang, Xinjie Wang, Haoran Ding, Yiran Li, Shuai Luo, Joseph Adu-Amankwaah and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yaru Liu *College of Life Sciences, Shandong Normal University, Jinan, China.
Linhui Xia *College of Clinical Medical, Jining Medical University, Jining, China.
Xiangyu WangCollege of Clinical Medical, Jining Medical University, Jining, China.
Wenxuan WangCollege of Stomatology, Jining Medical University, Jining, China.
Huizhu YangCollege of Clinical Medical, Jining Medical University, Jining, China.
Xinjie WangCollege of Clinical Medical, Jining Medical University, Jining, China.
Haoran DingCollege of Clinical Medical, Jining Medical University, Jining, China.
Yiran LiCollege of Medical Imaging and Laboratory, Jining Medical University, Jining, China.
Shuai LuoShandong Lifei Biological Group, Qingdao, China.
Joseph Adu-AmankwaahDepartment of Pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Jinxiang YuanLin He's Academician Workstation of New Medicine and Clinical Translation, Jining Medical University, Jining, China.
Rubin TanDepartment of Physiology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, China.
Kai MengLin He's Academician Workstation of New Medicine and Clinical Translation, Jining Medical University, Jining, China.
Jianping ZhuCollege of Life Sciences, Shandong Normal University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Normal physiological activity of the heart depends on the coordinated regulation of various ion channels in cardiomyocytes (CM), and dysfunction of these channels serves as a key pathological basis for cardiac diseases, including arrhythmias and heart failure Mitochondria play a central role in maintaining the cardiac redox balance and calcium (Ca

Indexed as

ADAMcalcium overloadcardiac ion channelheart diseasemitochondrial function

Identifiers

PMID42602110
PMCPMC13473694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.