ReviewFrontiers in bioengineering and biotechnology2026
Human relevant platforms for cutaneous wound healing research: current landscape, translational gaps, and emerging frontiers.
Review in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cutaneous wound healing is a dynamic, multicellular process that unfolds across four interrelated phases - haemostasis, inflammation, proliferation, and remodellingeach governed by precise intercellular signalling that remains incompletely understood in its human context. Animal models and two-dimensional cell cultures have shaped much of what we know about wound biology, yet both consistently fall short when the question moves from mechanism to translation. They fail to capture the structural organisation of human skin, the particular rhythms of human immune activation and resolution, and above all the multifactorial pathology that makes chronic wounds-diabetic foot ulcers especially, so resistant to treatment. This review traces the development of human-relevant alternative models as a coherent scientific response to those failures: from scratch assays and monocultures through to three-dimensional reconstructed equivalents, organoid platforms,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.