Evidence map›Paper›PMID 42601760›Full record

ArticleMedicine2026

A bibliometric and visual analysis of PRMTs research publications for cancer (2006-2024).

Mengjia Li, Lijing Zhan, Jinlin Cui, Xinle Liu, Liping Wang, Yangyang Han

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengjia LiDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Lijing ZhanDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Jinlin CuiDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Xinle LiuDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Liping WangDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Yangyang HanDepartment of Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.ORCID 0009-0005-9284-5530

Funding

Open Research Fund Project of Key Laboratory of High Incidence Disease Research in Xinjiang, Ministry of Education 2025B02
6 · The paper itself

Abstract

backgroundProtein arginine methyltransferases (PRMTs) have attracted considerable attention as potential targets for anticancer drug development. However, no bibliometric analysis of research articles on PRMTs in the field of oncology has been reported to date. To establish a knowledge map of PRMTs and cancer, summarize the current status and collaborative patterns of related publications, and explore research hotspots and future development prospects.

methodsUsing defined topic terms and their corresponding free-text terms, we searched the Web of Science Core Collection (WOSCC) database for relevant publications from January 1, 2006 to September 7, 2024. CiteSpace was used to perform bibliometric analyses of countries, institutions, authors, cited journals, keywords, and references. NoteExpress was used to import, manage, and add references.

resultsA total of 250 articles related to PRMTs and cancer were retrieved from WOSCC. Visual analysis showed a steady increase in the number of publications from 2006 to 2024. The United States had the highest centrality, whereas China had the highest publication count. The Chinese Academy of Sciences was the most productive institution. Mark T. Bedford was the most prominent and productive author. Cancer Cell had the highest centrality in this field. Based on keyword citation frequency, the leading research topics in current PRMTs and cancer studies were breast cancer, gene expression, coactivator-associated arginine methyltransferase 1 (CARM1), androgen receptor, and coactivator.

conclusionOverall, PRMTs and cancer research represents a promising research direction, and members of the PRMT family have potential utility as cancer biomarkers and therapeutic targets.

Indexed as

BibliometricsNeoplasmsProtein-Arginine N-MethyltransferasesHumansProtein-Arginine N-MethyltransferasesbibliometriccancerCiteSpaceco-occurrence analysisprotein arginine methyltransferases (PRMTs)

Identifiers

PMID42601760
PMCPMC13480914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.