Evidence map›Paper›PMID 42601701›Full record

ArticleMedicine2026

Association between habitual sleep duration and Alzheimer's disease: A cross-sectional study based on NHANES 2007-2018.

Guang Yang, Wenzhe Hou, Jiawen Wu, Xian Yang, Ye Yang, Qiqi Chen, Yanli Liu

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guang YangDepartment of Neurology, Kunshan Hospital of Traditional Chinese Medicine, Suzhou, China.
Wenzhe HouDepartment of Neurology, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China.
Jiawen WuDepartment of Neurology, Kunshan Hospital of Traditional Chinese Medicine, Suzhou, China.
Xian YangDepartment of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu Province, China.
Ye YangDepartment of Neurology, Kunshan Hospital of Traditional Chinese Medicine, Suzhou, China.
Qiqi ChenDepartment of Radiology, Kunshan Traditional Chinese Medicine Hospital, Kunshan, China.
Yanli LiuDepartment of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu Province, China.ORCID 0009-0009-5949-0634

Funding

Suzhou City Applied Basic Research and Science and Technology Innovation Project SYWD2024196the Kunshan Key Research and Development Program (Social Development) Project Fund KS2325
6 · The paper itself

Abstract

Given the potential importance of sleep disturbances in the pathophysiology of Alzheimer's disease (AD), as well as the fact that habitual sleep duration - an observable and modifiable lifestyle factor - has become a significant potential target for early risk warning of neurodegenerative diseases, this study utilizes data from the National Health and Nutrition Examination Survey to thoroughly examine the association between AD and habitual sleep patterns among adults in the United States. It aims to determine the correlations among sleep duration, Alzheimer's disease, and all-cause mortality, thereby providing population-based evidence for the early prevention and public health intervention of AD. Using a cross-sectional design, 29,692 participants were selected. A multiple logistic regression model was used to assess the association between sleep duration and Alzheimer's disease. Additionally, all-cause mortality status was derived from matched records obtained from the United States National Death Index. The Cox regression model was used to calculate the hazard ratios and 95% confidence intervals of all-cause mortality associated with the relationship between sleep duration and AD. Our analysis revealed a significant positive correlation between increased sleep time and AD prevalence, a relationship that persisted in the adjusted model. Subgroup analysis showed that this association remained consistent across different populations. This study clarifies the effectiveness of sleep time as a predictive tool for AD and underscores its importance in AD assessment. Based on the predictive value of sleep time, our study advocates incorporating body composition factors into AD risk assessment, thus expanding the scope of Alzheimer's disease prevention strategies.

Indexed as

Alzheimer DiseaseSleep DurationSleep Wake DisordersAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited StatesAll-cause mortalityAlzheimer’s diseaseNational Health and Nutrition Examination SurveyPublic HealthSleep time

Identifiers

PMID42601701
PMCPMC13480857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.