Evidence map›Paper›PMID 42601687›Full record

ReviewMedicine2026

Research progress on the effect of sericin on bone regeneration: A review.

Rui Wang, Jiatong Zou, Jiajun Xin, Yifei Dai, Xiantao Chen, Yushen Li, Bowei Wang, Zhihui Liu

Abstract readReview
In one paragraph

Review in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui WangSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Jiatong ZouSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Jiajun XinSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Yifei DaiSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Xiantao ChenSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Yushen LiSchool of Stomatology, Jilin University, Changchun, Jilin, China.
Bowei WangDepartment of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhihui LiuHospital of Stomatology, Jilin University, Changchun, Jilin, China.ORCID 0000-0001-8650-9104

Funding

he Medical and health industry development project 20220401102YYthe Medical and health 20230204076YYthe National Natural Science Foundation of China 82370934This research was funded by the Graduate Innovation Fund of Jilin University 2024CX143
6 · The paper itself

Abstract

Sericin is a waste material from the silk production process, researchers its found to have good biological activity and is widely used in tissue engineering. The aim of this paper is to summarize the biological applications of sericin in the field of bone tissue engineering and their research progress. Randomized controlled trials, prospective or retrospective clinical studies, case series and reports, and systematic evaluations. MEDLINE, PubMed, and Google Scholar were searched using keywords. Sericin, has the ability to promote cell proliferation and angiogenesis. It also has excellent bone regenerative properties such as promoting osteoblast differentiation. Sericin itself has excellent physicochemical properties and can be processed into materials with different properties for bone regeneration engineering. Bone defects due to various skeletal diseases or surgical needs, etc are a major challenge for clinical treatment. Modern tissue engineering using synthetic osteogenic active materials offers another therapeutic option for bone defects, and sericin is expected to play a greater role as a promising biological material.

Indexed as

Bone RegenerationSericinsTissue EngineeringAnimalsBiocompatible MaterialsCell DifferentiationCell ProliferationHumansOsteoblastsOsteogenesisBiocompatible MaterialsSericinsbone regenerationhistological engineeringsericin

Identifiers

PMID42601687
PMCPMC13480862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.