Dual-source mesoporous nanosilicas from horsetail plant and chemical precursors show structural and textural evidence for vitamin C loading and release.

Zahra Shabestari-Khiabani, Sara Fazli-Shokouhi, Soodabeh Davaran, Azin Yavari, Sahar Porrang, Maasoumeh Khatamian

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Zahra Shabestari-KhiabaniDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran.

Sara Fazli-ShokouhiAdvanced Materials Research Institute, Sahand University of Technology, Tabriz, Iran.

Soodabeh DavaranDepartment of Medical Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, 516661-4733, Iran.

Azin YavariDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran.

Sahar PorrangMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, 34596, Tuzla, Istanbul, Turkey.

Maasoumeh KhatamianDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran. Khatamian@tabrizu.ac.ir.ORCID 0000-0002-4405-1294

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6 · The paper itself

Abstract

This study focuses on the synthesis and characterization of a novel silica material from horsetail-derived bio-silica, modified via mesoporous structure generation (mesoporous bio-silica) and its subsequent application as a carrier for Ascorbic Acid (Vitamin C, VC) delivery. The synthesized material was systematically characterized using low-angle X-ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), Fourier Transform Infrared Spectroscopy (FTIR), and nitrogen adsorption/desorption isotherms of Brunauer-Emmett-Teller (BET). Raw bio-silica demonstrated an amorphous structure, confirmed by broad XRD peaks. Subsequent templating yielded a mesoporous silica structure exhibiting characteristic MCM-41 diffraction patterns. VC loading significantly altered the textural properties, notably reducing BET surface area and pore volume, which is consistent with pore blocking by VC. FTIR analysis confirmed the successful incorporation of VC through the appearance of characteristic C-H (2850, 2925 cm

Indexed as

Ascorbic AcidDrug CarriersSilicon DioxideAdsorptionDrug LiberationPorositySpectroscopy, Fourier Transform InfraredX-Ray DiffractionAscorbic AcidDrug CarriersSilicon DioxideDelivery systemsHorsetailMesoporous silicaPorous structureVitamin C

Identifiers

PMID42601373

DOI10.1038/s41598-026-63800-9

PMCPMC13476268

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