ReviewJornal de pediatria2026
Prevalence and risk factors of recurrent respiratory tract infections in preschool children: a systematic review and meta-analysis.
Review in Jornal de pediatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
objectiveTo evaluate the prevalence and risk factors for recurrent respiratory tract infections in preschool children.
methodsStudies on RRTIs in preschool children were retrieved from PubMed, Cochrane Library, Embase, Web of Science, CBM, CNKI, Wanfang, and VIP databases up to October 2025. Data was analyzed using Stata 15.0.
resultsTen studies involving 15,271 preschoolers were included. Meta-analysis showed that the overall prevalence was 24.14% [95% CI (0.23,0.33)].A total of 11 risk factors for RRTIs in preschool children were identified, including: asthma (I² = 93.8%) [OR = 3.84, 95% CI (1.97, 7.47), P < 0.001], allergy(I² = 0) [OR = 2.27, 95% CI (2.06, 2.51), P < 0.001], dietary bias (I² = 65%) [OR = 2.10, 95% CI (1.37, 3.24), P = 0.001], smoking co-resident(I² = 42.7%) [OR = 1.83, 95% CI (1.44, 2.32), P < 0.001], low parental education level(I² = 0) [OR = 3.17, 95% CI (1.76, 5.69), P < 0.001], initial use of antibiotics < 6 months(I² = 0) [OR = 1.70, 95% CI (1.50, 1.93), P < 0.001], maternal BMI per 3 kg/m² increment(I² = 0) [OR = 1.18, 95% CI (1.08, 1.28), P < 0.001], and breastfeeding duration < 6 months(I² = 0) [OR = 1.26, 95% CI (1.12, 1.42), P < 0.001].
conclusionThe high prevalence (24.14%) of RRTIs in preschool children and the risk factors identified provide evidence for targeted prevention and intervention strategies.
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