Evidence map›Paper›PMID 42600012›Full record

ArticleScience advances2026

Beyond the golden rule of polymer network dynamics: Design principles for tissue-mimetic viscoelasticity.

Emilie A Moses, Claire J Wang, Joseph Collins, Jessica Garcia, Josiah H Marshall, Andrey V Dobrynin, Sergei S Sheiko

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emilie A MosesDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0002-4570-9200
Claire J WangDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0009-5993-6683
Joseph CollinsDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0009-8960-345X
Jessica GarciaDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Josiah H MarshallDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0000-6362-9111
Andrey V DobryninDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-6484-7409
Sergei S SheikoDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-3672-1611

Funding

Development of injectable solvent-free tissue-mimetic platform for breast reconstructive surgeryR01EB038288 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Sergei Sheiko · 2025 to 2026
$1.1M
NIBIB NIH HHS R01 EB038288
6 · The paper itself

Abstract

Technologies ranging from transportation to biomedical devices rely on soft materials whose performance hinges on balancing stiffness and damping. In conventional polymer networks, however, these properties are typically coupled: Softer materials are intrinsically more dissipative, reflecting a long-standing correlation in polymer dynamics that severely restricts the accessible design space. Here, we move beyond this longstanding constraint using brush-like polymer networks whose architecture in combination with chemistry governs viscoelastic response. By independently tuning strand volume and flexibility, we vary the elastic modulus over orders of magnitude while maintaining nearly constant relaxation time without altering network chemistry. Our findings establish a general framework for encoding viscoelastic responses in polymer networks, enabling the design of tissue-mimetic materials with programmable equilibrium stiffness and rate-dependent dissipation.

Indexed as

Biomimetic MaterialsElasticityPolymersElastic ModulusViscosityPolymers

Identifiers

PMID42600012
PMCPMC13475476

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.