ArticleScience advances2026
Distinct types of dendritic Ca
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Active dendrites enrich single-neuron computations by performing nonlinear input integration, including generation of dendritic spikes. Diverse dendritic spike types have been found in various cortical neuron classes in vitro; however, their in vivo prevalence and roles remained elusive. We measured calcium activity in apical dendrites and soma of pyramidal cells in the hippocampal area CA3 (CA3PCs) during virtual navigation in mice. Although dendritic activity was generally synchronous with the soma, their correlation decreased with dendritic distance. We identified two types of regenerative dendritic activities: slow, large-amplitude global Ca
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