Ethylene-regulated dimeric ETR1 kinase reveals multi-site EIN2 docking targeted by peptides that delay climacteric ripening.

Zhendong He, Yifan Xu, Jinying Shi, Ze Ding, Peng Peng, Yongsen Chen, Qingshan Bill Fu, Wen Chen

Abstract read

In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhendong HeSchool of Food Science and Engineering, South China University of Technology, Guangzhou 510641, Guangdong, China.ORCID 0000-0003-1096-0630

Yifan XuSchool of Food Science and Engineering, South China University of Technology, Guangzhou 510641, Guangdong, China.ORCID 0009-0000-4734-5274

Jinying ShiSchool of Food Science and Engineering, South China University of Technology, Guangzhou 510641, Guangdong, China.

Ze DingSchool of Food Science and Engineering, South China University of Technology, Guangzhou 510641, Guangdong, China.

Peng PengGuangxi Subtropical Crops Research Institute, Nanning, Guangxi 530002, China.

Yongsen ChenGuangxi Subtropical Crops Research Institute, Nanning, Guangxi 530002, China.ORCID 0009-0007-2256-2118

Qingshan Bill FuZhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.ORCID 0000-0002-7445-2355

Wen ChenSchool of Food Science and Engineering, South China University of Technology, Guangzhou 510641, Guangdong, China.ORCID 0000-0001-7387-4532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ethylene receptors are ER membrane histidine kinases that repress ethylene responses, and the central transducer ETHYLENE INSENSITIVE 2 (EIN2) docks to receptors through its C-terminal tail. Here we express full-length

Indexed as

ArabidopsisArabidopsis ProteinsEthylenesPeptidesProtein KinasesProtein MultimerizationReceptors, Cell SurfaceBinding SitesMolecular Docking SimulationProtein BindingArabidopsis ProteinsEIN2 protein, ArabidopsisethyleneEthylenesETR1 protein, ArabidopsisPeptidesProtein KinasesReceptors, Cell Surface

Identifiers

PMID42599998

DOI10.1126/sciadv.aef8713

PMCPMC13475606

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.