Evidence map›Paper›PMID 42599635›Full record

ArticleChemistry & biodiversity2026

Phytochemical Profiling, Biological Evaluation, and Molecular Insights Into the Urease Inhibitory Potential of Fraxinus angustifolia Crude Extract and Fractions.

Sarra Belkhir, Meriem Rahmani-Berboucha, Sarah Sihem Zemam, Nadjet Debbache-Benaida, Fatma Duygu Ceylan, Nabil Adrar, Amina Atia, Naima Saidene, Nabila Benamrouche, Dina Atmani-Kilani and 1 more

Abstract read
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In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarra BelkhirLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Meriem Rahmani-BerbouchaLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Sarah Sihem ZemamLaboratory of Enterobacteria and Other Related Bacteria, Pasteur Institute of Algeria, Algiers, 16000, Algeria.ORCID https://orcid.org/0000-0002-0769-1823
Nadjet Debbache-BenaidaLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Fatma Duygu CeylanDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul, 34469, Turkey.
Nabil AdrarDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul, 34469, Turkey.ORCID https://orcid.org/0000-0003-3723-3003
Amina AtiaLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Naima SaideneLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Nabila BenamroucheLaboratory of Enterobacteria and Other Related Bacteria, Pasteur Institute of Algeria, Algiers, 16000, Algeria.
Dina Atmani-KilaniLaboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia, 06000, Algeria.
Esra CapanogluDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul, 34469, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fraxinus angustifolia Vahl. has long been used in traditional medicine for the management of inflammatory and gastrointestinal disorders. This study investigated the anti-urease, anti-Helicobacter pylori, and anti-inflammatory activities of the ethanolic leaf extract and its phenolic fractions, with a focus on the mechanisms underlying these effects. The extracts exhibited inhibition of urease activity and bacterial growth, with the aqueous fraction of chloroform (AC) showing the most pronounced effect (urease IC

Indexed as

Anti-Bacterial AgentsEnzyme InhibitorsFraxinusPhytochemicalsPlant ExtractsUreaseHelicobacter pyloriMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructurePlant LeavesStructure-Activity RelationshipAnti-Bacterial AgentsEnzyme InhibitorsPhytochemicalsPlant ExtractsUreaseanti‐urease activityFraxinus angustifoliaHPLC‐DADH. pyloripolyphenols

Identifiers

PMID42599635
PMCPMC13475581

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.