Evidence map›Paper›PMID 42599613›Full record

ArticleVisual computing for industry, biomedicine, and art2026

Mapping the generative era: a bibliometric and specialty-focused analysis of large language models in healthcare.

Jianding Peng, Yao Tuo, Gang Wang, Ruiqin Han, Qing Wang, Yi Wang, Zixin Hu, Xiaofei Hu

Abstract read
In one paragraph

Article in Visual computing for industry, biomedicine, and art, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianding Peng *Beijing Tongren Hospital, Capital Medical University, Beijing, 100086, China.
Yao Tuo *Department of Ophthalmology, Jiangbei Campus, First Affiliated Hospital of Army Medical University, Chongqing, 400038, China.
Gang WangChongqing Liangjiang New Area Traditional Chinese Medicine Hospital, Chongqing, 400038, China.
Ruiqin HanState Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100086, China.
Qing WangInstitute of Medical Information, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100086, China.
Yi WangSchool of Computer Science, Chongqing University, Chongqing, 400000, China. YiWang@cqu.edu.cn.
Zixin HuArtificial Intelligence Innovation and Incubation Institute, Fudan University, Shanghai, 200433, China. huzixin@fudan.edu.cn.
Xiaofei HuDepartment of Nuclear Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. harryzonetmmu@163.com.ORCID http://orcid.org/0000-0001-5376-2779

Funding

Fundamental Research Funds for the Central Universities 2023CDJYGRH-ZD06Informatization Teaching Reform Project of Chongqing Southwest Hospital 2025BKC16Senior Medical Talents Program of Chongqing for Young and Middle-aged Senior Medical Talents Program of Chongqing for Young and Middle-aged
6 · The paper itself

Abstract

Large language models (LLMs) have been rapidly adopted in healthcare since 2022; however, field-level trends and specialty differences remain poorly characterized. This study aims to map the research landscape of LLMs in healthcare and generate comparative specialty profiles through a bibliometric analysis using the Web of Science Core Collection (2015-2025), including English-language articles and reviews analyzed for publication and citation trends, leading countries, institutions, authors, journals, co-citation networks, and keyword structures with VOSviewer and CiteSpace, with sub-analyses for medicine, general and internal; surgery; and radiology, nuclear medicine and medical imaging. Of the 2226 articles included, the annual output increased from four publications in 2022 to 1327 in 2025, yielding a compound annual growth rate (CAGR) of 592.26%; the United States of America contributed 43.5% of the publications, followed by China (14.3%), Germany (9.2%), Turkey (9.0%), and England (6.8%); the publications for each specialty were surgery (31.7%), medicine, general and internal (24.2%), and radiology, nuclear medicine and medical Iimaging (13.0%), with the last demonstrating the fastest 2023-2024 growth (CAGR 265%); and the collaboration networks were United States of America-centered, with dense trans-Atlantic ties. LLM research in healthcare is expanding rapidly with distinct specialty-specific trajectories, and interpreting these trajectories using the DECIDE-AI (developmental and exploratory clinical Iinvestigations of decision support systems driven by artificial intelligence) framework clarifies low-risk near-term applications and monitoring priorities, providing a specialty-aware baseline to support the safe, equitable, and regulation-aligned adoption of LLMs in clinical practice.

Indexed as

Bibliometric analysisDECIDE-AIHealthcare applicationLarge language modelSpecialty-specific adoption (medicine, surgery, radiology)

Identifiers

PMID42599613
PMCPMC13476431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.