ArticleCVIR endovascular2026
Embolisation of simple PAVMs with high-volume detachable non-fibered coils: a 3-year follow-up study.
Article in CVIR endovascular, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo determine pulmonary arteriovenous malformation (PAVM) persistence and safety of high-volume detachable non-fibred (HVDNF) coil embolisation of de novo simple PAVMs using computed tomography pulmonary angiography (CTPA) at 6-month and 3-year follow-up.
methodsThis retrospective single-cohort study included patients who underwent embolisation of de novo simple PAVMs, exclusively with HVDNF coils, between January 2018 and January 2021. Primary endpoints were PAVM persistence at 6 months, cumulative persistence at 3 years and coil recanalisation at 6 months and 3 years. Secondary endpoints were technical success, safety, repeat embolisation and vein diameter reduction. Persistence and recanalisation were confirmed with digital subtraction angiography (DSA).
resultsThis study included 50 patients with 75 de novo PAVMs. PAVM persistence at 6 months was 13.2%; cumulative persistence at 3 years was 17.4%. Coil recanalisation was the persistence mechanism in 10.3% of the cases at 6 months; at 3 years, this was 13.0%. Technical success rate was 98.7%. There were no procedure- or PAVM-related serious adverse events. Repeat embolisation with HVDNF coils was performed in 4 PAVMs after 6 months and 5 PAVMs after 3 years. Mean vein diameter reduction was 38.3% (SD 29.4%) at 6 months and 44.6% (SD 36.5%) at 3 years.
conclusionsHVDNF coils are safe to use for de novo PAVM embolisation, show an excellent technical success rate and are associated with acceptable 6-month and 3-year persistence and coil recanalisation rates.
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