Evidence map›Paper›PMID 42599178›Full record

ArticleJournal of Zhejiang University. Science. B2026

Neuroprotection of engineered

Xin Fang, Yun Wang, Zhenli Long, Bin Liao, Bo Wang, Daojun Hong, Jie Luo, Tingtao Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin FangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Yun WangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Zhenli LongSchool of Queen Mary, Nanchang University, Nanchang 330031, China.
Bin LiaoDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Bo WangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Daojun HongDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Jie LuoSchool of Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330031, China. jieluo@ncu.edu.cn.
Tingtao ChenDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China. jieluo@ncu.edu.cn, chentingtao1984@163.com.

Funding

the Academic and Technical Leaders of Major Disciplines in Jiangxi Province 20213BCJL22049the Jiangxi Provincial Natural Science Foundation 20242BAB26134 and 20242BAB25464the National Natural Science Foundation of China 82060222 and 82460237
6 · The paper itself

Abstract

Parkinson's disease (PD) is a prevalent neurodegenerative disorder with limited therapeutic options and no cure, underscoring the urgent need for novel treatment strategies. Our previous work demonstrated that an engineered strain of

Indexed as

alpha-SynucleinClostridium butyricumGlucagon-Like Peptide 1Glycogen Synthase Kinase 3 betaParkinson DiseaseProto-Oncogene Proteins c-aktAnimalsDisease Models, AnimalGastrointestinal MicrobiomeIntestinal Barrier FunctionMaleMiceMice, Inbred C57BLMice, TransgenicNeuroprotectionPhosphatidylinositol 3-Kinasesalpha-SynucleinGlucagon-Like Peptide 1Glycogen Synthase Kinase 3 betaGsk3b protein, mousePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktClostridium butyricum-pMTL007-GLP-1Glucagon-like peptide-1 (GLP-1)Gut microbiotaParkinson’s diseasePI3K/AKT/GSK-3β pathway

Identifiers

PMID42599178
PMCPMC13474202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.