Evidence map›Paper›PMID 42599169›Full record

ArticleRadiology. Imaging cancer2026

Incremental Value of Synthetic MRI Radiomics in Predicting Neoadjuvant Response in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.

Siyi Chen, Yongxin Chen, Chen Jin, Bingjie Zheng, Shishen Ding, Zijin Weng, Wenjie Tang, Weifeng Liu, Yihong Lin, Qingcong Kong and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Imaging cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Siyi Chen *Department of Radiology, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China.
Yongxin Chen *Department of Radiology, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China.
Chen JinCollege of Computer Science and Technology, Zhejiang University of Technology, Zhejiang, China.
Bingjie ZhengDepartment of Radiology, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-5408-7680
Shishen DingDepartment of Radiology, Liuzhou People's Hospital, Guangxi Medical University, Liuzhou, China.
Zijin WengDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Wenjie TangDepartment of Radiology, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China.ORCID 0000-0002-9752-4948
Weifeng LiuDepartment of Radiology, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China.
Yihong LinDepartment of Information, Southern Medical University Shunde Hospital, Foshan, China.
Qingcong KongDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Qianwei Zhou *College of Computer Science and Technology, Zhejiang University of Technology, Zhejiang, China.
Yuan Guo *Department of Radiology, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China.ORCID 0000-0001-5115-1624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To evaluate the added value of a synthetic radiomics model (S-Radiomics) that integrates topologic and Hessian-based features with traditional radiomic features for predicting a pathologic complete response (pCR) in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Materials and Methods Patients with HER2-positive breast cancer from three centers were retrospectively included between January 2018 and January 2024. Patients from centers 1 and 2 (

Indexed as

Breast NeoplasmsMagnetic Resonance ImagingNeoadjuvant TherapyRadiomicsAdultErb-b2 Receptor Tyrosine KinasesFemaleHumansMiddle AgedPathologic Complete ResponsePredictive Value of TestsRetrospective StudiesERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesBreastBreast CancerHuman Epidermal Growth Factor Receptor 2MRINeoadjuvant ChemotherapyPathologic Complete ResponseRadiogenomicsRadiomics

Identifiers

PMID42599169
PMCPMC13620322

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.