Evidence map›Paper›PMID 42599000›Full record

ArticleTransboundary and emerging diseases2026

Resolving the Phylogenetic Placement of the FSfaCV/PCV5-Related Viruses Within the Genus Macochavirus.

Wenqiang Wang, Liping Jiang, Tingting Niu, Miaojie Zhang, Lulu Chen, Xiaoye Jia, Lin Yuan, Kegong Tian, Xiangdong Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenqiang WangJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China, yzu.edu.cn.ORCID https://orcid.org/0009-0006-7873-0929
Liping JiangJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China, yzu.edu.cn.
Tingting NiuBeijing Sino-science Gene Technology Co., Ltd., Beijing 102629, China.
Miaojie ZhangBeijing Sino-science Gene Technology Co., Ltd., Beijing 102629, China.
Lulu ChenBeijing Sino-science Gene Technology Co., Ltd., Beijing 102629, China.
Xiaoye JiaBeijing Sino-science Gene Technology Co., Ltd., Beijing 102629, China.
Lin YuanBeijing Sino-science Gene Technology Co., Ltd., Beijing 102629, China.
Kegong TianNational Research Center for Veterinary Medicine, Luoyang 471000, China.
Xiangdong LiJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China, yzu.edu.cn.ORCID https://orcid.org/0000-0002-4635-1602

Funding

111 Project D18007National Key Research and Development Program of China 2023YFD1800500National Natural Science Foundation of China 32500538Priority Academic Program Development of Jiangsu Higher Education Institutions
6 · The paper itself

Abstract

Metagenomic analysis of fecal samples from diarrheic pigs in China identified 10 complete circular single-stranded DNA viral genomes previously designated as putative porcine circovirus 5 (PCV5)-like viruses. Genome characterization revealed a typical cressdnavirus organization with bidirectionally oriented Rep and Cap genes. Phylogenetic analyses based on complete genomes and encoded proteins showed that these viruses do not cluster with members of Circoviridae but instead form a distinct lineage within the family Pecoviridae, closely related to the genus Macochavirus. Sequence identity, genetic distance, and nucleotide diversity analyses supported their classification as a coherent viral group. Comparative analyses indicated greater sequence divergence in the Rep region than in the Cap region. These findings support reclassification of putative PCV5 as a porcine-associated lineage within the genus Macochavirus, designated porcine Macochavirus (PMV), thereby resolving their long-standing taxonomic ambiguity and expanding the recognized diversity of cressdnaviruses within the family Pecoviridae.

Indexed as

DNA VirusesPhylogenySwine DiseasesAnimalsChinaCircovirusGenome, ViralSwinecressdnavirushigh-throughput metagenomic sequencingPecoviridaeporcine Macochavirusvirus taxonomy

Identifiers

PMID42599000
PMCPMC13475009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.