SynthesisCartilage2026
High Variability in Return-to-Sport Assessment After Autologous Chondrocyte Implantation of the Knee: A Systematic Review.
Synthesis in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PurposeTo systematically review return-to-sport (RTS) patient-reported outcome measure (PROM) usage following autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI). We hypothesized that RTS reporting would be highly inconsistent, limiting clinical applicability.MethodsA systematic review was conducted using PubMed, Embase, and Scopus (January 1, 2014-December 8, 2024). Eligible studies reported RTS PROMs after ACI/MACI. Extracted data included study design, demographics, name and type of scale used, and assessment modality.ResultsOf 807 studies screened, 85 met inclusion criteria. Measures used to report RTS varied widely. The Knee injury and Osteoarthritis Outcome Score-Sport/Rec and the International Knee Documentation Committee Subjective Knee Evaluation Form were the most commonly reported validated PROMs, included in 71.8% and 49.4% of studies, respectively. Only 15.3% of studies reported RTS as a postoperative percentage. Of all, 22.4% of studies used custom, nonvalidated tools. Most studies (49.4%) were prospective, and in-person evaluation was most common (52.8%). Timepoints of RTS measurement were inconsistent.ConclusionsRTS is inconsistently quantified following ACI/MACI, limiting cross-study comparisons and complicating clinical interpretation of outcomes. Standardized use of and expansion of validated PROMs is needed to improve the clinical applicability of data on RTS for ACI/MACI.
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