ArticleCureus2026
Extragonadal Seminoma: Simultaneous Involvement of the Anterior Mediastinum and Central Nervous System.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of a 20-year-old male who presented with a two-month history of progressively worsening binocular diplopia, dizziness, chest tightness, and significant weight gain. A comprehensive evaluation, including serial imaging, biopsy, and cerebrospinal fluid analysis, ultimately led to the diagnosis of an extragonadal seminoma with simultaneous involvement of the anterior mediastinum and the brain. Notably, the patient had a longstanding history of nonspecific testicular microlithiasis. The patient exhibited a favorable clinical and radiological response to treatment with whole-brain radiation combined with BEP (cisplatin, etoposide, bleomycin) chemotherapy. This rare presentation, together with the positive therapeutic outcome, provides meaningful insights into the existing literature on extragonadal germ cell tumors, particularly regarding atypical metastatic patterns, diagnostic challenges, therapeutic considerations, and prognosis in complex clinical scenarios.
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Registered trials
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