ArticleAnnals of cardiothoracic surgery2026
The aortic window: a temporal framework for acute type A aortic dissection.
Article in Annals of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Aorta Is One Organ; Our Response Is Not: A Global Case for Systems Redesign in Acute Aortic Syndromes.Journal of clinical medicine · 2026Review
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute type A aortic dissection (ATAAD) is a surgical emergency with time-dependent mortality. Surgical outcomes in high-volume centers are excellent, yet population-level outcomes remain catastrophic. This gap reflects a systems failure in recognition, diagnosis, and coordination rather than surgical inadequacy, and no formal time-based pathway currently governs care from emergency presentation to surgery. Methods: Current epidemiology, international guidelines, registry evidence, and national audit data were synthesized, together with the structure of established time-critical pathways in ST-elevation myocardial infarction, stroke, major trauma, and sepsis, and multidisciplinary and patient-and-public input, to derive a temporal framework for ATAAD. The framework is advanced as a hypothesis for formal international consensus validation rather than an empirically validated standard. Results: The proposed framework, the aortic window, is a phased pathway from emergency-department (ED) arrival to first surgical incision, structured as RACE (four acute phases: REACH, ALERT, CONVEY, ESCALATE) and RESTORE (recovery and lifelong surveillance), and operationalized through a named activation protocol. ED-to-incision time is the principal whole-system endpoint, chosen because it captures pre-diagnosis delay that diagnosis-anchored metrics exclude. Process and outcome measures are defined at case level with scheduled network review, aligned to established national audit registries. Implementation is staged and incorporates an education and run-in period before performance assessment. Conclusions: The aortic window reframes ATAAD as a system-level, time-critical emergency amenable to the organizational solutions that improved outcomes in other time-dependent conditions. The proposed targets require prospective evaluation but provide a structured, measurable basis for coordinated pathway improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.