ReviewAnnals of cardiothoracic surgery2026
Normothermic frozen elephant trunk surgery without circulatory arrest: is this the future?
Review in Annals of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frozen elephant trunk (FET) repair has expanded the treatment of complex aortic arch pathology but continues to rely on hypothermic circulatory arrest (HCA), which remains a major physiological limitation of the procedure. In this Keynote, we describe our current normothermic FET strategy, designed to perform arch reconstruction under continuous cerebral and systemic perfusion, through the integration of open and endovascular techniques. Retrograde stent-graft deployment and balloon occlusion within the prosthesis allow controlled distal aortic clamping while maintaining uninterrupted systemic circulation. In our initial experience, the technique was technically feasible and associated with acceptable perioperative hemodynamic and metabolic profiles; however, given the limited clinical experience, these findings should be interpreted as preliminary and require further evaluation. Beyond its technical aspects, this approach reflects a conceptual shift in arch surgery from mitigating the consequences of circulatory arrest to pursuing strategies aimed at avoiding it. In selected patients, normothermic FET may represent a physiologically oriented option within the ongoing evolution of contemporary aortic arch repair.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.